View abstract. The body breaks down caffeine to get rid of it. Rees K, Allen D, Lader M. The influences of age and caffeine on psychomotor and cognitive function. Smits, P., Corstens, F. H., Aengevaeren, W. R., Wackers, F. J., and Thien, T. False-negative dipyridamole-thallium-201 myocardial imaging after caffeine infusion. Products containing guarana are possibly safe when taken by mouth and for a short period of time. and other names. If you take products that contain caffeine and you take lithium, stop taking caffeine products slowly. Taking guarana along with alcohol might cause too much caffeine in the bloodstream and caffeine side effects including jitteriness, headache, and fast heartbeat. Taking these antibiotics along with guarana can increase the risk of side effects including jitteriness, headache, increased heart rate, and other side effects. Eur J Clin Pharmacol 1985;28:425-8. J.Ethnopharmacol. Lithium tremor and caffeine intake: two cases of drinking less and shaking more. Schechter MD, Timmons GD. It has been shown that guarana contains 4-6 times more caffeine than something like the coffee bean we are very accustomed to consuming through a morning cup of coffee. Polyphenols from guaraná after in vitro digestion: evaluation of bioacessibility and inhibition of activity of carbohydrate-hydrolyzing enzymes. Stimulant drugs speed up the nervous system. View abstract. Inhibition and reversal of platelet aggregation by methyl xanthines. The frequency of caffeine withdrawal in a population-based survey and in a controlled, blinded pilot experiment. American Academy of Pediatrics. View abstract. 1983;24(1):93-98. 1998;60(2):111-116. View abstract. Dews PB, O'Brien CP, Bergman J. Caffeine: behavioral effects of withdrawal and related issues. View abstract. Rapuri PB, Gallagher JC, Kinyamu HK, Ryschon KL. View abstract. Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. Do not take guarana without medical advice if you are using any of the following medications: stimulant drugs (amphetamines, ephedrine, nicotine, others); medications for depression or mental disorders; medications that slow blood-clotting: ardeparin (Normiflo), aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), dipyridamole (Persantine), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others; any antibiotics or medication for fungal infections; This list is not complete. 1-26-1978;298(4):181-186. View abstract. For the purposes of fat loss, guarana is rarely used on its own. A., and Antolin, M. A. Risk-factors for Parkinson's disease: case-control study in the province of Caceres, Spain. A comparison of the central nervous system effects of caffeine and theophylline in elderly subjects. You may not be able to use guarana if you have certain medical conditions. It belongs to the Sapindaceae family, which also contains the flowering plants horse chestnut, lychee, and maple. View abstract. View abstract. Pharmacol Exp Ther 1997;282:1465-72. Obesity is … It is sometimes found on top of or in places of regular caffeine. View abstract. Guarana is a plant that hails from The Amazon Basin in Brazil. Pharmacol Biochem Behav 2004;79(3):401-411. View abstract. View abstract. View abstract. Effects of caffeine on human health. Guarana is a stimulant, due to it's caffeine content. Tobias JD. Bone status among postmenopausal women with different habitual caffeine intakes: a longitudinal investigation. Am J Clin Nutr 2004;80:22-8. Benowitz NL, Osterloh J, Goldschlager N, et al. The caffeine in guarana might also speed up the nervous system. View abstract. 2015 Jul 27;7(8):6109-27. View abstract. View abstract. View abstract. View abstract. Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? View abstract. Stop consuming guarana or other caffeine-containing products at least 24 hours before a cardiac stress test. Because it’s high in caffeine, guarana has become a popular energy supplement. Habitual caffeine intake and the risk of hypertension in women. Ann Intern Med. View abstract. sorbilis (Mart.) DiPiro JT, Talbert RL, Yee GC, et al; eds. Eur J Clin Pharmacol 2000;56:537-44.. View abstract. If you need a cardiac stress test you should stop taking guarana at least 24 hours before your test. Seizure activity and unresponsiveness after hydroxycut ingestion. Fatal caffeine poisoning (case from practice). Carbo M, Segura J, De la Torre R, et al. Keep in mind that natural products are not always necessarily safe and dosages can be important. Pola, J., Subiza, J., Armentia, A., Zapata, C., Hinojosa, M., Losada, E., and Valdivieso, R. Urticaria caused by caffeine. 2000;3(3):253-261. Some antibiotics might decrease how quickly the body breaks down caffeine. Belliardo, F., Martelli, A., and Valle, M. G. HPLC determination of caffeine and theophylline in Paullinia cupana Kunth (guarana) and Cola spp. Epidemiology 2008;19:55-62. 1991;88(4):680-681. Moderate to heavy caffeine consumption during pregnancy and relationship to spontaneous abortion and abnormal fetal growth: a meta-analysis. Riluzole (Rilutek) interacts with GUARANA. View abstract. Guarana is a plant and it is also known as Brazilian Cocoa, Cacao Brésilien, Guarana Seed Extract, Guaranine, Paullinia cupana, Paullinia sorbilis, Zoom. Watson JM, Sherwin RS, Deary IJ, et al. Caffeine withdrawal increases lithium blood levels. This survey is being conducted by the WebMD marketing sciences department. Adenosine (Adenocard) interacts with GUARANA. Wrenn, K. D. and Oschner, I. Rhabdomyolysis induced by a caffeine overdose. Biochem.Pharmacol 5-18-1994;47(10):1767-1776. The body breaks down clozapine (Clozaril) to get rid of it. JAMA 2005;294:2330-5. Also known as “Brazilian cocoa,” guarana is a South American plant whose seeds’ caffeine content is a whopping two-to-five times that of coffee beans. A randomized, double-blind, placebo-controlled, cross-over study. Savitz DA, Chan RL, Herring AH, et al. View abstract. Howell LL, Coffin VL, Spealman RD. J Pharmacokinet.Biopharm. Andersen T, Fogh J. The mechanism of weight loss facilitated by guarana extract supplements in athletes is extrapolated from data which examines the “fat burning” effects of guarana consumption in sedentary and exercising rats. Birth control pills can decrease how quickly the body breaks down caffeine. Daniel, W. A., Syrek, M., Rylko, Z., and Kot, M. Effects of phenothiazine neuroleptics on the rate of caffeine demethylation and hydroxylation in the rat liver. Barbour, K. E., Zmuda, J. M., Strotmeyer, E. S., Horwitz, M. J., Boudreau, R., Evans, R. W., Ensrud, K. E., Petit, M. A., Gordon, C. L., and Cauley, J. Haller, C. A., Jacob, P., and Benowitz, N. L. Short-term metabolic and hemodynamic effects of ephedra and guarana combinations. Med J Aust 2001;174:520-1. View abstract. Aviat.Space Environ.Med. Guarana has large leaves and clusters of flowers and is best known for the seeds from its fruit, which are about the size of a coffee bean. View abstract. Stopping caffeine too quickly can increase the side effects of lithium. 1983;11(2):109-126. Mattei, R., Dias, R. F., Espinola, E. B., Carlini, E. A., and Barros, S. B. Guarana (Paullinia cupana): toxic behavioral effects in laboratory animals and antioxidants activity in vitro. View abstract. View abstract. Purified dry Paullinia cupana (PC-18) extract for chemotherapy-induced fatigue: results of two double-blind randomized clinical trials. Chen, Y., Xiao, C. Q., He, Y. J., Chen, B. L., Wang, G., Zhou, G., Zhang, W., Tan, Z. R., Cao, S., Wang, L. P., and Zhou, H. H. Genistein alters caffeine exposure in healthy female volunteers. The Rancho Bernardo Study. Influence of mexiletine on caffeine elimination. Available at: https://books.nap.edu/books/0309082587/html/index.html. View abstract. View abstract. Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This information may not fit your specific health circumstances. Astrup, A., Toubro, S., Cannon, S., Hein, P., Breum, L., and Madsen, J. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. View abstract. 2009 Apr;15(4):431-3. Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients. Antibiotics (Quinolone antibiotics) interacts with GUARANA. Am J Cardiol 2004;93:343-6. What is Guarana? View abstract. View abstract. 1988;21(3):535-538. It is named for the Guarani tribe in the Amazon, who used its seeds to brew a drink. Basic Clin Pharmacol Toxicol 2004;94:13-8. It's a member of the Sapindaceae family of plants which includes such members as the maple tree, horse chestnut, and lychee. South Med J 2000;93:297-304. The effects of caffeine on simulated driving, subjective alertness and sustained attention. Nevertheless, it's worth digging into what is proven (and not). Xanthine interference with dipyridamole-thallium-201 myocardial imaging. Guarana may also be used for purposes not listed in this product guide. Taking guarana with these medications used for depression might cause serious side effects including fast heartbeat, high blood pressure, nervousness, and others. 1987;41(1):25-30. Parsons, W. D. and Pelletier, J. G. Delayed elimination of caffeine by women in the last 2 weeks of pregnancy. Pharmacother 1995;29:425-7. Food Chem Toxicol 2017;109:585-648. Pomportes L, Davranche K, Brisswalter I, Hays A, Brisswalter J. Presse Med 2-3-2001;30(4):166-167. Mexiletine (Mexitil) interacts with GUARANA. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Vandeberghe K, Gillis N, Van Leemputte M, et al. Verapamil (Calan, Covera, Isoptin, Verelan) can decrease how quickly the body gets rid of caffeine. What factors influenced or will influence your purchase? Caffeine works similarly to theophylline. Guarana is a shrub whose seeds are very rich in caffeine—it contains about two to three times the caffeine content of most coffee beans. Disulfiram (Antabuse) can decrease how quickly the body gets rid of caffeine. Hansen, S. A., Folsom, A. R., Kushi, L. H., and Sellers, T. A. View abstract. Select one or more newsletters to continue. 2000;96(1):85-89. Caballero, T., Garcia-Ara, C., Pascual, C., Diaz-Pena, J. M., and Ojeda, A. Urticaria induced by caffeine. Fernandes O, Sabharwal M, Smiley T, et al. Cimetidine (Tagamet) can decrease how quickly your body breaks down caffeine. Guarana is used for weight loss, to enhance athletic performance, as a stimulant, and to reduce mental and physical fatigue. Conlisk, A. J. and Galuska, D. A. View abstract. McGowan JD, Altman RE, Kanto WP Jr. Neonatal withdrawal symptoms after chronic maternal ingestion of caffeine. 2000;31(5):562-568. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Other drugs may interact with guarana, including prescription and over-the-counter medicines, vitamins, and herbal products. Greenway FL, Raum WJ, DeLany JP. Haskell CF, Kennedy DO, Wesnes KA, Milne AL, Scholey AB. South Med J 1988;81:1092-4.. View abstract. Eur J Clin Pharmacol 1989;37:279-83. 2010;64(5):483-489. By speeding up the nervous system, stimulant medications can make you feel jittery and increase your heart rate. Sette CVM, Ribas de Alcântara BB, Schoueri JHM, et al. Guarana contains caffeine. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . Pharmacol Biochem.Behav. Am.J Vet.Res. Fluconazole (Diflucan) might decrease how quickly the body gets rid of caffeine Taking guarana along with fluconazole (Diflucan) might increase the risk of caffeine side effects such as nervousness, anxiety, and insomnia. Washington, DC: National Academy Press, 2001. Am J Clin Nutr 2001;74:569-70. Some antibiotics that decrease how quickly the body breaks down caffeine include ciprofloxacin (Cipro), enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), sparfloxacin (Zagam), trovafloxacin (Trovan), and grepafloxacin (Raxar). Clin Pharmacol Ther 1983;33(5):591-602. No abstract available. Am.J.Clin.Nutr. View abstract. 1996;203(1):95-98. noun 1 mass noun A substance prepared from the seeds of a Brazilian shrub, used as a tonic or stimulant. Hodgson JM, Puddey IB, Burke V, et al. Generic Name: guarana (GWAR ah na)Brand Name: Medically reviewed by Drugs.com on Jul 24, 2020. View abstract. Is caffeine a risk factor for bone loss in the elderly? Hartter, S., Nordmark, A., Rose, D. M., Bertilsson, L., Tybring, G., and Laine, K. Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity. Suleman A, Siddiqui NH. View abstract. Food Addit Contam 2003;20:1-30. Lloyd T, Johnson-Rollings N, Eggli DF, et al. Caffeine ingestion increases the insulin response to an oral-glucose-tolerance test in obese men before and after weight loss. View abstract. Information from this source is evidence-based and objective, and without commercial influence. Store at room temperature away from moisture and heat. Galduroz, J. C. and Carlini, Ede A. Medications for depression (MAOIs) interacts with GUARANA. The caffeine in guarana might also speed up the nervous system. Ali M, Afzal M. A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. Wakabayashi K, Kono S, Shinchi K, et al. Ferrini RL, Barrett-Connor E. Caffeine intake and endogenous sex steroid levels in postmenopausal women. View abstract. Clin Pharmacokinet 2000;39:127-53. Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Do not use excessive guarana if you are breast-feeding a baby. Fluvoxamine (Luvox) interacts with GUARANA. View abstract. Yu, G., Maskray, V., Jackson, S. H., Swift, C. G., and Tiplady, B. 2007;64(11):965-967. View abstract. Pharmacol Rep. 2009;61(5):851-858. Interpretation of Diagnostic Tests. Taking guarana along with ephedrine might cause too much stimulation and sometimes serious side effects and heart problems. View abstract. J Am Diet Assoc 2000;100:1368-80. Some research shows that taking guarana can reduce feelings of tiredness in some people undergoing. View abstract. Petrie HJ, Chown SE, Belfie LM, et al. Drinking alcohol with this product can cause side effects including jitteriness, headache and fast heartbeat. Pak.J Biol Sci 5-1-2009;12(9):734-737. The berries themselves are extremely similar in composition to coffee beans, and although the chemicals in the berries are slightly different, they have the same basic effect as caffeine at about the same dose level. Guarana has become very well known as a highly effective tonic plant, thanks in no small part to the fact that it contains 4 … Metabolism 2007;56(12):1694-1698. Effectiveness of guarana (Paullinia cupana) for postradiation fatigue and depression: results of a pilot double-blind randomized study. Khodesevick AP. Guarana is one of the numerous superfood ingredients infused into both Bondi Coffee's high performance coffee blends, so we thought we’d take you through the benefits of this super seed extract. Taking guarana along with fluvoxamine (Luvox) might cause too much caffeine in the body, and increase the effects and side effects of caffeine. 1991;32(8):1538-1541. Available at: https://cerhr.niehs.nih.gov/common/caffeine.html. 2010;11:49. The body breaks down the caffeine in guarana to get rid of it. Guarana (Paullinia cupana) is a plant which has intoxicant, anti-cancer, antibacterial, enhance athletic performance, reduce mental and physical fatigue and weight loss effects properties which make it useful in the medicinal era. Guarana contains more than 2.5% to 5% caffeine by weight. Medicinal use of this product has not been approved by the FDA. Pentobarbital (Nembutal) interacts with GUARANA. The Washington Post. Parsons, W. D. and Neims, A. H. Effect of smoking on caffeine clearance. Cochrane Database Syst Rev 2001;4:CD001112.. View abstract. Cleve Clin J Med 2002;69:449-50. Palma CG, Lera AT, Lerner T, de Oliveira MM, de Borta TM, Barbosa RP, Brito GM, Guazzelli CA, Cruz FJ, del Giglio A. Guarana (Paullinia cupana) Improves Anorexia in Patients with Advanced Cancer. Philadelphia, PA: Lippincott Williams & Wilkins; 1998. Reprod Toxicol 1998;12:435-44. Sao Paulo Med.J. 2007 Jan;21(1):65-70. Taking guarana along with verapamil (Calan, Covera, Isoptin, Verelan) can increase the risk of caffeine side effects including jitteriness, headache, and an increased heartbeat. Guarana contains caffeine. The transfer of drugs and other chemicals into human milk. Clin Sci (Lond) 2003;104:447-54. The caffeine in guarana might block the affects of adenosine (Adenocard). The effect of fluconazole on the pharmacokinetics of caffeine in young and elderly subjects. Farmakol Toksikol 1956;19(suppl):62. Chamone, D. A., Silva, M. I., Cassaro, C., Bellotti, G., Massumoto, C. M., and Fujimura, A. Y. Guaraná (Paullinia cupana) inhibits aggregation in whole blood. A. 1993;3(3):160-162. The body breaks down caffeine (contained in guarana) to get rid of it. Jha, R. M., Mithal, A., Malhotra, N., and Brown, E. M. Pilot case-control investigation of risk factors for hip fractures in the urban Indian population. Am J Epidemiol 1996:144:642-4. Guarana is a plant and it is also known as Brazilian Cocoa, Cacao Brésilien, Guarana Seed Extract, Guaranine, Paullinia cupana, Paullinia sorbilis, Zoom. View abstract. You may report side effects to FDA at 1-800-FDA-1088. Association of coffee and caffeine intake with the risk of parkinson disease. The body breaks down caffeine to get rid of it. Altern Med Rev 2005;10(4):321-325. View abstract. Bell DG, Jacobs I, Ellerington K. Effect of caffeine and ephedrine ingestion on anaerobic exercise performance.